Chronic treatment of Acute Hepatic Porphyria

The PBS subsidises givosiran for the chronic treatment of Acute Hepatic Porphyria (AHP).

Patient eligibility

The Pharmaceutical Benefits Scheme (PBS) subsidises treatment with givosiran under the National Health Act 1953, section 85 for the chronic treatment of AHP.

Patients must be eligible for the PBS and meet the relevant restriction criteria.

The Schedule of Pharmaceutical Benefits on the PBS website outlines the restrictions for prescribing givosiran.

Treatment specifics

To be eligible for initial PBS-subsidised treatment with givosiran, treatment must be initiated under the supervision of a healthcare professional experienced in the management of porphyria.

To be eligible for continuing PBS-subsidised treatment with givosiran, patients must be treated by, or in consultation with a healthcare professional experienced in the management of porphyria.

Authority applications

Applying for initial treatment

Please note: You don’t need to complete this application in writing when you request PBS authority online.

Applications for initial authority approval to prescribe PBS-subsidised givosiran for the chronic treatment of AHP can be made:

All written applications must include:

Applying for continuing treatment

Please note: You’ll get an immediate assessment when you request PBS authorities online.

Applications for continuing authority approval to prescribe PBS-subsidised givosiran for the chronic treatment of AHP can be made in:

All written applications must include:

More information

Call the PBS Complex Drugs Programs enquiry line for more information.

Page last updated: 1 April 2026.
QC 83859