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Patient eligibility
The Pharmaceutical Benefits Scheme (PBS) subsidises treatment with eflornithine under the National Health Act 1953, section 100 for patients with high-risk neuroblastoma.
Patients must be eligible for the PBS and meet the relevant restriction criteria.
The Schedule of Pharmaceutical Benefits on the PBS website outlines the restrictions for prescribing eflornithine.
Section 100 arrangements
eflornithine
This item is only PBS-subsidised for non-admitted patients, day admitted patients, or patients on discharge who are attending either:
- an approved private hospital
- a public hospital.
This item isn’t PBS-subsidised for public hospital in-patients. You must include the hospital name and provider number on the authority application form.
Treatment specifics
To be eligible for PBS-subsidised treatment with eflornithine, patients must be treated by either a:
- paediatric oncologist
- haematologist.
Authority applications
Applying for initial treatment
Please note: You’ll get an immediate assessment when you request PBS authorities online.
Applications for initial authority approval to prescribe PBS-subsidised eflornithine to treat high-risk neuroblastoma can be made:
- using the Online PBS Authorities system
- in writing and use HPOS Form upload
- in writing and mail to PBS Complex Drugs Programs.
All written applications must include:
- details of the proposed prescription or prescriptions
- the completed high-risk neuroblastoma - eflornithine - initial authority application form
- relevant attachments.
Applying for initial grandfather treatment
For patients who received non-PBS-subsidised eflornithine treatment before 1 August 2025 for high-risk neuroblastoma, apply for initial grandfather authority approval either:
- in real time using the Online PBS Authorities system
- by calling the PBS Complex Drugs Programs enquiry line.
Applying for continuing treatment
Applications for continuing authority approval to prescribe PBS-subsidised eflornithine to treat high-risk neuroblastoma can be made either:
- in real time using the Online PBS Authorities system
- by calling the PBS Complex Drugs Programs enquiry line.
More information
Call the PBS Complex Drugs Programs enquiry line for more information.