Changes to Pharmaceutical Benefits Scheme (PBS) for selinexor

Published: 1 October 2025

As of 1 October 2025, selinexor (Xpovio) has been updated to a PBS General Schedule Highly Specialised Drug.

The change affects how you manage selinexor (Xpovio) prescriptions.

Community pharmacies who dispense a public hospital prescription for selinexor (Xpovio) will get a PBS rejection code 734. However, your patient’s prescription remains valid but must now be dispensed by a public hospital pharmacy.

If you’re a PBS approved prescriber, please call the PBS General Authorities to get a telephone approval.

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Page last updated: 1 October 2025.
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